Loeng // Lecture „Biomedical implications of the defective autophagy–NAD axis in iPSC-derived neuronal models of Wolfram syndrome“

30.septembril kell 10 
Biomeedikumis Ravila 19-0093

Eesti doktorikooli Arsti- ja terviseteaduste, veterinaaria haru raames peab kaasprofessor Sovan Sarkar loengu teemal „Biomedical implications of the defective autophagy–NAD axis in iPSC-derived neuronal models of Wolfram syndrome“.

Sovan Sarkar on Birminghami ülikooli vähi- ja genoomiteaduste instituudi kaasprofessor, kelle peamine uurimisvaldkond on autofaagia ning autofaagia roll ja reguleerimine inimsüsteemis ja selle dereguleerimine inimeste haiguste, sealhulgas neurodegeneratsiooni patoloogias. Tema loeng keskendub autofaagia rolli uurimisele haruldase neurodegeneratiivse haiguse Wolframi sündroomi patoloogias, kasutades Wolframi sündroomi pluripotentsete tüvirakkude mudelsüsteemi. Täpsemalt kirjeldab ta häirunud autofaagia-NAD-telge Wolframi sündroomi pluripotentsetest tüvirakkudest tuletatud neuronaalsetes mudelites.

Kontakt: marite.punapart@ut.ee

September 30 at 10AM
Biomedicum, Ravila 19-0093, Tartu

Within the Estonian Doctoral School for Medical and Health Sciences, Veterinary Medicine, Associate Professor Sovan Sarkar will give a lecture titled „Biomedical implications of the defective autophagy–NAD axis in iPSC-derived neuronal models of Wolfram syndrome“.

Sovan Sarkar is an Associate Professor, Institute of Cancer and Genomic Sciences, University of Birmingham, whose main research interest is a biological process called autophagy and the role and regulation of autophagy in the human system and its deregulation in diseases, including neurodegeneration. The lecture will focus on understanding the role of autophagy in the pathology of Wolfram syndrome, a rare progressive neurodegenerative disorder, utilizing induced pluripotent stem cell (iPSC) models of Wolfram syndrome. Specifically, he describes a defective autophagy-NAD axis in iPSC-derived neuronal models of Wolfram syndrome.

Contact: marite.punapart@ut.ee