{"id":4747,"date":"2026-03-24T14:31:23","date_gmt":"2026-03-24T12:31:23","guid":{"rendered":"https:\/\/www.doktorikool.ee\/?post_type=tribe_events&#038;p=4747"},"modified":"2026-03-27T08:57:55","modified_gmt":"2026-03-27T06:57:55","slug":"seminar-reproduktiivmeditsiinis-seemnerakkude-mutageneesi-mustrid-ja-moju-meie-genofondile","status":"publish","type":"tribe_events","link":"https:\/\/www.doktorikool.ee\/et\/uritused\/seminar-reproduktiivmeditsiinis-seemnerakkude-mutageneesi-mustrid-ja-moju-meie-genofondile\/","title":{"rendered":"Seminar reproduktiivmeditsiinis \u201eSeemnerakkude\u00a0mutageneesi\u00a0mustrid ja m\u00f5ju\u00a0meie genofondile\u201c\u00a0"},"content":{"rendered":"<div  class=\"tribe-events-schedule tribe-clearfix\" >\n\t<p class=\"tribe-events-schedule__datetime\">\n\t\t<span class=\"tribe-events-schedule__date tribe-events-schedule__date--start\">\n\t\t\t17\/04\t\t<\/span>\n\n\t\t\t\t\t<span class=\"tribe-events-schedule__separator tribe-events-schedule__separator--date\">\n\t\t\t\t \t\t\t<\/span>\n\t\t\t<span class=\"tribe-events-schedule__time tribe-events-schedule__time--start\">\n\t\t\t\t14:00\t\t\t<\/span>\n\t\t\n\t\t\t\t\t\t\t\t\t<span class=\"tribe-events-schedule__separator tribe-events-schedule__separator--time\">\n\t\t\t\t\t &#8211; \t\t\t\t<\/span>\n\t\t\t\n\t\t\t\t\t\t\t<span class=\"tribe-events-schedule__time tribe-events-schedule__time--end\">\n\t\t\t\t\t15:30\t\t\t\t<\/span>\n\t\t\t\n\t\t\t\t\t\t<\/p>\n<\/div>\n\n\n\n<p>\ud83d\udccd <strong>Biomeedikum Ravila 19, Tartu, ruum BM-1006<\/strong>&nbsp;<\/p>\n\n\n\n<p>Osalema on oodatud k\u00f5ik huvilised.<\/p>\n\n\n\n<p>Sugurakkudes tekkivad uusmutatsioonid v\u00f5ivad p\u00f5hjustada&nbsp;kaass\u00fcndinud&nbsp;arenguh\u00e4ireid, kusjuures enamik neist&nbsp;DNA koodi&nbsp;muutustest toimub&nbsp;spermatogeneesi&nbsp;k\u00e4igus. Loeng&nbsp;k\u00e4sitleb uusi&nbsp;teadmisi&nbsp;mutageneesi&nbsp;kohta,&nbsp;mida on saadud&nbsp;nn.&nbsp;trio-p\u00f5hisel (ema-isa-laps) genoomide v\u00f5rdleval j\u00e4rjestamisel&nbsp;ning&nbsp;spermide&nbsp;geneetilise profiili&nbsp;s\u00fcvauuringutel.&nbsp;Mutatsioonide teke,&nbsp;kuhjumine&nbsp;ja&nbsp;klonaalne&nbsp;selektsioon&nbsp;spermatogoonides&nbsp;kujundavad&nbsp;k\u00fcpsete&nbsp;spermide&nbsp;genofondi, m\u00f5jutades ka&nbsp;p\u00e4rilike&nbsp;haigustega seotud&nbsp;geenivariantide&nbsp;esinemissagedust.&nbsp;<\/p>\n\n\n\n<p>Loengut viib l\u00e4bi <strong>Dr.&nbsp;Raheleh&nbsp;Rahbari<\/strong> (Wellcome&nbsp;Sanger&nbsp;Institute,&nbsp;\u00dchendkuningriik). Raheleh&nbsp;Rahbari&nbsp;on uurimisr\u00fchma juht&nbsp;Wellcome&nbsp;Sanger&nbsp;Institute-is, kus tema teadust\u00f6\u00f6 keskendub mutatsiooniprotsesside m\u00f5istmisele inimese suguliinis ning nende m\u00f5jule p\u00e4rilikkusele ja haigustele.&nbsp;Tema t\u00f6\u00f6 \u00fchendab suuremahulist genoomikat ja tipptasemel&nbsp;sekveneerimistehnoloogiaid, et uurida, kuidas mutatsioonid tekivad, kuhjuvad ja valitakse sugurakkudes.&nbsp;Ta on eriti huvitatud sellest, kuidas suguliini ja keharakkude (soma) vahelised vastastikm\u00f5jud kujundavad mutatsioonimustreid kogu inimese eluea jooksul ning kuidas need protsessid m\u00f5jutavad arenguh\u00e4irete riski.<br>Tema publikatsioonide listi leiab <span style=\"text-decoration: underline;\"><a href=\"https:\/\/www.sanger.ac.uk\/person\/rahbari-raheleh\/\" data-type=\"link\" data-id=\"https:\/\/www.sanger.ac.uk\/person\/rahbari-raheleh\/\" target=\"_blank\" rel=\"noreferrer noopener\">siit<\/a><\/span>.<\/p>\n\n\n\n<p>Registreeru <strong><span style=\"text-decoration: underline;\"><a href=\"https:\/\/forms.office.com\/e\/7p88gthHcE\" data-type=\"link\" data-id=\"https:\/\/forms.office.com\/e\/7p88gthHcE\" target=\"_blank\" rel=\"noreferrer noopener\">SIIN<\/a><\/span><\/strong>. Registreerimise t\u00e4htaeg on <strong>17. aprill 2026<\/strong>.<\/p>\n\n\n\n<p>K\u00fcsimuste korral palum p\u00f6\u00f6rduda professor Maris Laane poole (<a href=\"mailto:maris.laan@ut.ee\" target=\"_blank\" rel=\"noreferrer noopener\"><span style=\"text-decoration: underline;\">maris.laan@ut.ee<\/span><\/a>).<\/p>\n\n\n\n<p>Eesti doktorikooli arsti- ja terviseteaduste, veterinaaria haru.<\/p>\n\n\n\t<div  class=\"tribe-block tribe-block__events-link\" >\n\t\t<div class=\"tribe-events tribe-common\">\n\t\t\t<div class=\"tribe-events-c-subscribe-dropdown__container\">\n\t\t\t\t<div class=\"tribe-events-c-subscribe-dropdown\">\n\t\t\t\t\t<div class=\"tribe-common-c-btn-border tribe-events-c-subscribe-dropdown__button\">\n\t\t\t\t\t\t<svg\n\t class=\"tribe-common-c-svgicon tribe-common-c-svgicon--cal-export tribe-events-c-subscribe-dropdown__export-icon\" \taria-hidden=\"true\"\n\tviewBox=\"0 0 23 17\"\n\txmlns=\"http:\/\/www.w3.org\/2000\/svg\"\n>\n\t<path fill-rule=\"evenodd\" 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7\"\n\txmlns=\"http:\/\/www.w3.org\/2000\/svg\"\n>\n\t<path fill-rule=\"evenodd\" clip-rule=\"evenodd\" d=\"M1.008.609L5 4.6 8.992.61l.958.958L5 6.517.05 1.566l.958-.958z\" class=\"tribe-common-c-svgicon__svg-fill\"\/>\n<\/svg>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"tribe-events-subscribe-dropdown-content\" class=\"tribe-events-c-subscribe-dropdown__content\">\n\t\t\t\t\t\t<ul class=\"tribe-events-c-subscribe-dropdown__list\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"tribe-events-c-subscribe-dropdown__list-item tribe-events-c-subscribe-dropdown__list-item--gcal\">\n\t\t\t\t\t\t\t\t\t<a\n\t\t\t\t\t\t\t\t\t\thref=\"https:\/\/www.google.com\/calendar\/event?action=TEMPLATE&#038;dates=20260417T140000\/20260417T153000&#038;text=Seminar%20reproduktiivmeditsiinis%20%E2%80%9ESeemnerakkude%C2%A0mutageneesi%C2%A0mustrid%20ja%20m%C3%B5ju%C2%A0meie%20genofondile%E2%80%9C%C2%A0&#038;details=%3Cp%3E%F0%9F%93%8D+%3Cstrong%3EBiomeedikum+Ravila+19%2C+Tartu%2C+ruum+BM-1006%3C%2Fstrong%3E%26nbsp%3B%3C%2Fp%3E+%3Cp%3EOsalema+on+oodatud+k%C3%B5ik+huvilised.%3C%2Fp%3E+%3Cp%3ESugurakkudes+tekkivad+uusmutatsioonid+v%C3%B5ivad+p%C3%B5hjustada%26nbsp%3Bkaass%C3%BCndinud%26nbsp%3Barenguh%C3%A4ireid%2C+kusjuures+enamik+neist%26nbsp%3BDNA+koodi%26nbsp%3Bmuutustest+toimub%26nbsp%3Bspermatogeneesi%26nbsp%3Bk%C3%A4igus.+Loeng%26nbsp%3Bk%C3%A4sitleb+uusi%26nbsp%3Bteadmisi%26nbsp%3Bmutageneesi%26nbsp%3Bkohta%2C%26nbsp%3Bmida+on+saadud%26nbsp%3Bnn.%26nbsp%3Btrio-p%C3%B5hisel+%28ema-isa-laps%29+genoomide+v%C3%B5rdleval+j%C3%A4rjestamisel%26nbsp%3Bning%26nbsp%3Bspermide%26nbsp%3Bgeneetilise+profiili%26nbsp%3Bs%C3%BCvauuringutel.%26nbsp%3BMutatsioonide+teke%2C%26nbsp%3Bkuhjumine%26nbsp%3Bja%26nbsp%3Bklonaalne%26nbsp%3Bselektsioon%26nbsp%3Bspermatogoonides%26nbsp%3Bkujundavad%26nbsp%3Bk%C3%BCpsete%26nbsp%3Bspermide%26nbsp%3Bgenofondi%2C+m%C3%B5jutades+ka%26nbsp%3Bp%C3%A4rilike%26nbsp%3Bhaigustega+seotud%26nbsp%3Bgeenivariantide%26nbsp%3Besinemissagedust.%26nbsp%3B%3C%2Fp%3E+%3Cp%3ELoengut+viib+l%C3%A4bi+%3Cstrong%3EDr.%26nbsp%3BRaheleh%26nbsp%3BRahbari%3C%2Fstrong%3E+%28Wellcome%26nbsp%3BSanger%26nbsp%3BInstitute%2C%26nbsp%3B%C3%9Chendkuningriik%29.+Raheleh%26nbsp%3BRahbari%26nbs%3C%2Fp%3E+%28View+Full+event+Description+Here%3A+https%3A%2F%2Fwww.doktorikool.ee%2Fet%2Furitused%2Fseminar-reproduktiivmeditsiinis-seemnerakkude-mutageneesi-mustrid-ja-moju-meie-genofondile%2F%29&#038;trp=false&#038;ctz=Europe\/Tallinn&#038;sprop=website:https:\/\/www.doktorikool.ee\/et\"\n\t\t\t\t\t\t\t\t\t\tclass=\"tribe-events-c-subscribe-dropdown__list-item-link\"\n\t\t\t\t\t\t\t\t\t\ttarget=\"_blank\"\n\t\t\t\t\t\t\t\t\t\trel=\"noopener noreferrer nofollow noindex\"\n\t\t\t\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\tGoogle Calendar\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"tribe-events-c-subscribe-dropdown__list-item tribe-events-c-subscribe-dropdown__list-item--ical\">\n\t\t\t\t\t\t\t\t\t<a\n\t\t\t\t\t\t\t\t\t\thref=\"\"\n\t\t\t\t\t\t\t\t\t\tclass=\"tribe-events-c-subscribe-dropdown__list-item-link\"\n\t\t\t\t\t\t\t\t\t\ttarget=\"_blank\"\n\t\t\t\t\t\t\t\t\t\trel=\"noopener noreferrer nofollow noindex\"\n\t\t\t\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\tiCalendar\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"tribe-events-c-subscribe-dropdown__list-item tribe-events-c-subscribe-dropdown__list-item--outlook-365\">\n\t\t\t\t\t\t\t\t\t<a\n\t\t\t\t\t\t\t\t\t\thref=\"\"\n\t\t\t\t\t\t\t\t\t\tclass=\"tribe-events-c-subscribe-dropdown__list-item-link\"\n\t\t\t\t\t\t\t\t\t\ttarget=\"_blank\"\n\t\t\t\t\t\t\t\t\t\trel=\"noopener noreferrer nofollow noindex\"\n\t\t\t\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\tOutlook 365\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"tribe-events-c-subscribe-dropdown__list-item tribe-events-c-subscribe-dropdown__list-item--outlook-live\">\n\t\t\t\t\t\t\t\t\t<a\n\t\t\t\t\t\t\t\t\t\thref=\"\"\n\t\t\t\t\t\t\t\t\t\tclass=\"tribe-events-c-subscribe-dropdown__list-item-link\"\n\t\t\t\t\t\t\t\t\t\ttarget=\"_blank\"\n\t\t\t\t\t\t\t\t\t\trel=\"noopener noreferrer nofollow noindex\"\n\t\t\t\t\t\t\t\t\t>\n\t\t\t\t\t\t\t\t\t\tOutlook Live\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n","protected":false},"excerpt":{"rendered":"<p>\ud83d\udccd Biomeedikum Ravila 19, Tartu, ruum BM-1006&nbsp; Osalema on oodatud k\u00f5ik huvilised. Sugurakkudes tekkivad uusmutatsioonid v\u00f5ivad p\u00f5hjustada&nbsp;kaass\u00fcndinud&nbsp;arenguh\u00e4ireid, kusjuures enamik neist&nbsp;DNA koodi&nbsp;muutustest toimub&nbsp;spermatogeneesi&nbsp;k\u00e4igus. Loeng&nbsp;k\u00e4sitleb uusi&nbsp;teadmisi&nbsp;mutageneesi&nbsp;kohta,&nbsp;mida on saadud&nbsp;nn.&nbsp;trio-p\u00f5hisel (ema-isa-laps) genoomide v\u00f5rdleval j\u00e4rjestamisel&nbsp;ning&nbsp;spermide&nbsp;geneetilise [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"template":"","meta":{"inline_featured_image":false,"_EventAllDay":false,"_EventTimezone":"Europe\/Tallinn","_EventStartDate":"2026-04-17 14:00:00","_EventEndDate":"2026-04-17 15:30:00","_EventStartDateUTC":"2026-04-17 11:00:00","_EventEndDateUTC":"2026-04-17 12:30:00","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"$","_EventCurrencyCode":"USD","_EventCurrencyPosition":"prefix","_EventDateTimeSeparator":" ","_EventTimeRangeSeparator":" - ","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_tribe_events_status":"","_tribe_events_status_reason":"","footnotes":""},"tags":[27],"tribe_events_cat":[13],"class_list":["post-4747","tribe_events","type-tribe_events","status-publish","hentry","tag-arsti-ja-terviseteadused","tribe_events_cat-kommunikatsioon","cat_kommunikatsioon"],"_links":{"self":[{"href":"https:\/\/www.doktorikool.ee\/et\/wp-json\/wp\/v2\/tribe_events\/4747","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.doktorikool.ee\/et\/wp-json\/wp\/v2\/tribe_events"}],"about":[{"href":"https:\/\/www.doktorikool.ee\/et\/wp-json\/wp\/v2\/types\/tribe_events"}],"author":[{"embeddable":true,"href":"https:\/\/www.doktorikool.ee\/et\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":4,"href":"https:\/\/www.doktorikool.ee\/et\/wp-json\/wp\/v2\/tribe_events\/4747\/revisions"}],"predecessor-version":[{"id":4789,"href":"https:\/\/www.doktorikool.ee\/et\/wp-json\/wp\/v2\/tribe_events\/4747\/revisions\/4789"}],"wp:attachment":[{"href":"https:\/\/www.doktorikool.ee\/et\/wp-json\/wp\/v2\/media?parent=4747"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.doktorikool.ee\/et\/wp-json\/wp\/v2\/tags?post=4747"},{"taxonomy":"tribe_events_cat","embeddable":true,"href":"https:\/\/www.doktorikool.ee\/et\/wp-json\/wp\/v2\/tribe_events_cat?post=4747"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}