Lecture "Alternative splicing and gene expression signatures of cellular stress and senescence"

Ravila 19-0089, Tartu

Nuno Barbosa-Morais (Gulbenkian Institute for Molecular Medicine, Portugal) is a computational biologist, having graduated in Physics Engineering and holding a PhD in Biomedical Sciences from the University of Lisbon.

After a decade of international research at the universities of Cambridge and Toronto, he was awarded an EMBO Installation Grant and established the Disease Transcriptomics Lab in 2015, based at the Gulbenkian Institute for Molecular Medicine in Lisbon.

They aim at understanding how transcriptional changes in human tissues increase proneness to disease, using bioinformatic analyses of genomes and transcriptomes. They also develop bioinformatics apps for assisting non-computational scientists in their analyses of transcriptomic data.

Nuno is also a Guest Associate Professor at the University of Lisbon, where he teaches Computational Biology and Critical Thinking to Master’s programs in Biomedical Engineering, Oncobiology and Biomedical Research.

In this lecture, Nuno will portray his team’s latest efforts in defining robust transcriptomic markers of human cell stress and senescence and their regulation. Nuno will also describe how they use such markers to leverage the wealth of publicly available human tissue and cancer transcriptomes to preliminarily test hypotheses about the role of cell stress in human pathologies.

In case of questions please turn to Eva Mõtte, eva.motte@ut.ee

Estonian Doctoral School for Medical and Health Sciences, Veterinary Medicine.